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8-Hydroxy-2'-deoxyguanosine

8-Hydroxy-2'-deoxyguanosine (8-OHdG) 是致癌反应和氧化应激的关键生物标志物。

CAS号

88847-89-6

分子式

C10H13N5O5

主要靶点

Endogenous Metabolite

仅限科研使用

Cat No : CM02010

Print datasheet

Synonyms

8-Oxo-2'-deoxyguanosine|8-Oxo-dG|8-OH-脱氧鸟嘌呤|8 Oxo dG|2'-Deoxy-8-oxoguanosine|8 OHdG|8-Hydroxydeoxyguanosine|8-Hydroxy-2-Deoxyguanosine|8-OHdG

验证数据展示

  • CAS No.: 88847-89-6

    8-Hydroxy-2'-deoxyguanosine
    CAS#: 88847-89-6

产品信息

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.

CAS号 88847-89-6
分子式 C10H13N5O5
主要靶点 Endogenous Metabolite
主要通路 代谢
分子量 283.24
纯度 97.13%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 8-Oxo-2'-deoxyguanosine|8-Oxo-dG|8-OH-脱氧鸟嘌呤|8 Oxo dG|2'-Deoxy-8-oxoguanosine|8 OHdG|8-Hydroxydeoxyguanosine|8-Hydroxy-2-Deoxyguanosine|8-OHdG

溶解度

DMSO:25 mg/ml(353.06 mM)

参考文献

1.Szymańska B, Długosz A. The role of the BLCA-4 nuclear matrix protein in bladder cancer. Postepy Hig Med Dosw (Online). 2017 Aug 13;71(1):681-689. Review.
2.Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):120-39.
3.Hallberg LM, Ward JB Jr, Wickliffe JK, Ameredes BT. Advanced Collaborative Emissions Study Auxiliary Findings on 2007-Compliant Diesel Engines: A Comparison With Diesel Exhaust Genotoxicity Effects Prior to 2007. Environ Health Insights. 2017 Jun 19;11:1178630217714215.
4.Dąbrowska N, Wiczkowski A. Analytics of oxidative stress markers in the early diagnosis of oxygen DNA damage. Adv Clin Exp Med. 2017 Jan-Feb;26(1):155-166.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2