验证数据展示
产品信息
26564-1-PBS targets ABCA1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | ABCA1 fusion protein Ag24118 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | ATP-binding cassette, sub-family A (ABC1), member 1 |
别名 | CERP, ATP-binding cassette transporter 1, ATP-binding cassette sub-family A member 1, ATP-binding cassette 1, ABC-1 |
计算分子量 | 2261 aa, 254 kDa |
观测分子量 | 250 kDa |
GenBank蛋白编号 | BC141816 |
基因名称 | ABCA1 |
Gene ID (NCBI) | 19 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O95477 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABCA, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABCA subfamily. Members of the ABCA subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway.