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验证数据展示

  • WB analysis of Jurkat using 17570-1-AP (same clone as 17570-1-PBS)

    WB analysis of Jurkat using 17570-1-AP (same clone as 17570-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 17570-1-AP (ACAP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17570-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 17570-1-AP (same clone as 17570-1-PBS)

    IF Staining of SH-SY5Y using 17570-1-AP (same clone as 17570-1-PBS)

    Immunofluorescent analysis of (10% Formaldehyde) fixed SH-SY5Y cells using 17570-1-AP (ACAP3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 17570-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ACAP3 Polyclonal antibody, PBS Only

ACAP3 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 17570-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

KIAA1716, Cnt-b5, CENTB5, Centaurin-beta-5, Centaurin beta 5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

17570-1-PBS targets ACAP3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ACAP3 fusion protein Ag11777 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
别名 KIAA1716, Cnt-b5, CENTB5, Centaurin-beta-5, Centaurin beta 5
计算分子量 834 aa, 92 kDa
观测分子量85kda, 92 kDa
GenBank蛋白编号BC047001
基因名称 ACAP3
Gene ID (NCBI) 116983
RRIDAB_2257668
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96P50
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ACAP3 (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3) , also known as CENTB5, is a protein-coding gene that belongs to the ACAP family of GTPase-activating proteins (GAPs). ACAP3 is involved in neuronal migration in the developing cerebral cortex of mice. Knockdown of ACAP3 in the developing cortical neurons of mice in utero significantly abrogated neuronal migration in the cortical layer, ACAP3 is involved in neuronal migration in the developing cerebral cortex of mice. Knockdown of ACAP3 in the developing cortical neurons of mice in utero significantly abrogated neuronal migration in the cortical layer (PMID: 28919417),