验证数据展示
产品信息
26834-1-PBS targets ACMSD in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | IHC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | ACMSD fusion protein Ag25230 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | aminocarboxymuconate semialdehyde decarboxylase |
Synonyms | |
Calculated Molecular Weight | 38 kDa |
GenBank Accession Number | BC016018 |
Gene Symbol | ACMSD |
Gene ID (NCBI) | 130013 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q8TDX5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ACMSD (alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase ) is the key enzyme that regulates the de novo NAD+ synthesis from tryptophan. ACMSD is highly expressed in the liver, kidney and to a lower degree in brain under physiological conditions. The enzyme is primarily cytosolic and is positioned at a critical branching point in the kynurenine pathway, wherein it influences the fate of the precursor 2-amino-3-carboxymuconic-6-semialdehyde (ACMS).