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ACP6 Polyclonal antibody

ACP6 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 32084-1-AP

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 32084-1-AP

    WB analysis using 32084-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 32084-1-AP (ACP6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA2780 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

32084-1-AP targets ACP6 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen ACP6 fusion protein Ag34812 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name acid phosphatase 6, lysophosphatidic
Synonyms
Calculated Molecular Weight 428 aa, 49 kDa
Observed Molecular Weight43 kDa
GenBank Accession NumberBC034686
Gene Symbol ACP6
Gene ID (NCBI) 51205
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NPH0
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Lysophosphatidic acid phosphatase type 6 (ACP6) is an LPA-specific acid phosphatase that hydrolyzes LPA to monoacylglycerol (MAG) and phosphate. Previous studies have shown that ACP6 is localized in the mitochondria with ubiquitous expression throughout all tissues, and high expression levels in kidney, heart, small intestine, muscle, and liver. Through specifi cally hydrolyzing LPA, ACP6 regulates mitochondrial lipid biosynthesis, thereby controlling important mitochondrial functions. It was also shown that ACP6 might be involved in tumor progression, suggesting that ACP6 could be a good candidate marker for the prognosis of esophageal cancer. Uniprot showed that by alternative splicing, ACP6 may have two kinds of shear fragments with molecular weights of 49 and 31kDa respectively. (PMID: 23807634)

实验方案

Product Specific Protocols
WB protocol for ACP6 antibody 32084-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols