验证数据展示
经过测试的应用
Positive WB detected in | mouse brain tissue, rat brain tissue |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:2000-1:10000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
13847-1-AP targets ACSL6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | ACSL6 fusion protein Ag4817 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | acyl-CoA synthetase long-chain family member 6 |
Synonyms | LACS 6, FACL6, EC:6.2.1.3, EC:6.2.1.15, Arachidonate--CoA ligase |
Calculated Molecular Weight | 78 kDa |
Observed Molecular Weight | 74 kDa |
GenBank Accession Number | BC047453 |
Gene Symbol | ACSL6 |
Gene ID (NCBI) | 23305 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9UKU0 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ACSL6 (Acyl-CoA Synthetase Long Chain Family Member 6) is a long-chain lipoyl-coenzyme A synthetase that is mainly responsible for catalyzing the binding of long-chain fatty acids to coenzyme A to form acyl-coenzyme A (Acyl-CoA). ACSL6 is involved in fatty acid metabolic transporter and the synthesis of cell membrane phospholipids, which affects the cell structure and function. ACSL6 plays an extremely important role in the pathogenesis of cancers such as hepatocellular carcinoma, lung cancer and neuroblastoma, suggesting that it may serve as a biomarker and therapeutic target for cancer therapy.
实验方案
Product Specific Protocols | |
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WB protocol for ACSL6 antibody 13847-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |