验证数据展示
发表文章中的应用
| WB | See 1 publications below |
产品信息
22216-1-AP targets ADAM19 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human |
| 免疫原 | ADAM19 fusion protein Ag17544 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ADAM metallopeptidase domain 19 (meltrin beta) |
| 别名 | ADAM 19, ADAM19, FKSG34, MADDAM, Meltrin beta, MLTNB |
| 计算分子量 | 955 aa, 105 kDa |
| 观测分子量 | 70 kDa |
| GenBank蛋白编号 | BC024214 |
| 基因名称 | ADAM19 |
| Gene ID (NCBI) | 8728 |
| RRID | AB_2879034 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H013 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Meltrinβ(ADAM19) is a metalloprotease-disintegrin expressed in the peripheral nervous system and other organs during embryogenesis. Its specific patterns of expression during embryogenesis suggest that it is involved in the development of the peripheral nervous system, skeletal muscle, bone and heart tissue(PMID:12482604). It participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell.