CoraLite®594-conjugated Angiotensinogen/AGT Monoclonal antibody

Angiotensinogen/AGT Monoclonal Antibody for
Cat No. CL594-68020

产品说明书

CloneNo. 1B2F5

宿主/亚型

Mouse / IgG2b

种属反应性

human, pig

应用

AGT, Angiotensinogen, Serpin A8, SERPINA8, 1B2F5

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  {{ptg:cur_Conjugation}}
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy AGT Ready-To-Use IHC Kit. AGT primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 68020-1-Ig

产品信息

CL594-68020 targets Angiotensinogen/AGT in applications and shows reactivity with human, pig samples.

经测试应用 Application Description
经测试反应性 human, pig
免疫原 Angiotensinogen/AGT fusion protein Ag16658 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
别名 AGT, Angiotensinogen, Serpin A8, SERPINA8, 1B2F5
计算分子量 485 aa, 53 kDa
观测分子量52 kDa
GenBank蛋白编号BC011519
基因名称 AGT
Gene ID (NCBI) 183
RRIDAB_2934793
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP01019
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene also have been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

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