验证数据展示
产品信息
15642-1-AP targets AID in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA Application Description |
| Tested Reactivity | human, mouse, rat |
| Immunogen | AID fusion protein Ag8136 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | activation-induced cytidine deaminase |
| Synonyms | AICDA, AID, ARP2, CDA2, Cytidine aminohydrolase, HIGM2 |
| Calculated Molecular Weight | 198 aa, 24 kDa |
| Observed Molecular Weight | 48-52 kDa |
| GenBank Accession Number | BC006296 |
| Gene Symbol | AIDA/AID |
| Gene ID (NCBI) | 57379 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9GZX7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
AID is essential to all three genetic alterations required for antigen-specific immunoglobulin: class switch recombination (CSR), somatic bypermutation (SHM), and gene conversion. Expression of AID is normally restricted to B cells in the GC, where SHM and CSR occur. It is likely these represent AID monomer and homodimer that western blot detected two bands in purified AID from nuclear extracts, one at 52 kDa and the other at 26 kDa. (PMID:16280388)