ALDH1A3-IN-3

ALDH1A3-IN-3 (化合物 16) 是一种有效的 ALDH1A3 抑制剂,IC50 值为 0.26 μM。ALDH1A3-IN-3 也是 ALDH3A1 的底物。ALDH1A3-IN-3 可用于前列腺癌的研究。

CAS号

18962-05-5

分子式

C10H12O2

主要靶点

Dehydrogenase

仅限科研使用

Cat No : CM13955

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Synonyms



产品信息

ALDH1A3-IN-3 (compound 16) is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate. ALDH1A3-IN-3 can be used for the research of prostate cancer.

CAS号 18962-05-5
分子式 C10H12O2
主要靶点 Dehydrogenase
主要通路 代谢
分子量 164.2
纯度 98.74%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件
别名

体外活性

ALDH1A3-IN-3 showed weak antiproliferative Effect against PC3, LNCaP, and DU145 PCa Cell Lines with IC50 ﹥200μM[1].

溶解度

DMSO:90mg/mL (548.1mM),Sonification is recommended.

参考文献

1.Ibrahim AIM, et, al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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