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ALDH2 modulator 1

ALDH2 modulator 1 是一种有效的且具有口服活性的乙醛脱氢酶-2 （ALDH2）调节剂。ALDH2 modulator 1 可使小鼠血液中的酒精含量降低。

CAS号

1629615-99-1

分子式

C18H18ClFN2O3

主要靶点

Dehydrogenase

仅限科研使用

Cat No : CM19909

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Synonyms

验证数据展示

  • CAS No.: 1629615-99-1

    ALDH2 modulator 1
    CAS#: 1629615-99-1

产品信息

ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.

CAS号 1629615-99-1
分子式 C18H18ClFN2O3
主要靶点 Dehydrogenase
主要通路 代谢
分子量 364.8
纯度 98.07%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件
别名

体内活性

ALDH2 modulator 1 (compound 161) (10 mg/kg for i.v.; 40, 60 mg/kg for p.o.) reduces blood alcohol levels in mice treated with oral administration of 5 g/kg alcohol.[1]

溶解度

DMSO:3.65 mg/mL (10 mM)

参考文献

1.Wenjin Yang, et al. Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof. WO2014160185A2.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2