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  • Featured Product
  • KD/KO Validated

ALR Polyclonal antibody, PBS Only

ALR Polyclonal Antibody for WB, IHC, IF-P, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF-P, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11293-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 11293-1-AP (same clone as 11293-1-PBS)

    WB analysis using 11293-1-AP (same clone as 11293-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11293-1-AP (ALR antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11293-1-PBS in a different storage buffer formulation.

  • WB analysis of HepG2 using 11293-1-AP (same clone as 11293-1-PBS)

    WB analysis of HepG2 using 11293-1-AP (same clone as 11293-1-PBS)

    WB result of ALR antibody (11293-1-AP; 1:40000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ALR transfected HepG2 cells. This data was developed using the same antibody clone with 11293-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 11293-1-AP (same clone as 11293-1-PBS)

    IHC staining of human liver cancer using 11293-1-AP (same clone as 11293-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11293-1-AP (ALR antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11293-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 11293-1-AP (same clone as 11293-1-PBS)

    IHC staining of human liver cancer using 11293-1-AP (same clone as 11293-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11293-1-AP (ALR antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11293-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse liver using 11293-1-AP (same clone as 11293-1-PBS)

    IP experiment of mouse liver using 11293-1-AP (same clone as 11293-1-PBS)

    IP result of anti-ALR (IP:11293-1-AP, 3ug; Detection:11293-1-AP 1:1000) with mouse liver tissue lysate 4000ug. This data was developed using the same antibody clone with 11293-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 11293-1-AP (same clone as 11293-1-PBS)

    IF Staining of mouse kidney using 11293-1-AP (same clone as 11293-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse kidney tissue using ALR antibody (11293-1-AP) at dilution of 1:200 and CoraLite®647-conjugated AffiniPure F(ab. This data was developed using the same antibody clone with 11293-1-PBS in a different storage buffer formulation.

产品信息

11293-1-PBS targets ALR in WB, IHC, IF-P, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF-P, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen ALR fusion protein Ag1840 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name growth factor, augmenter of liver regeneration
Synonyms
Calculated Molecular Weight 15 kDa, 23 kDa
Observed Molecular Weight 23-25 kDa
GenBank Accession NumberBC028348
Gene Symbol GFER
Gene ID (NCBI) 2671
RRIDAB_2109970
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP55789
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GFER (FAD-linked sulfhydryl oxidase) is also named as ALR, HERV1, HPO. It plays an important role in the disulfide relay system (DRS) in human mitochondria. The GFER gene codes for 2 distinct isoforms that are probably synthesized from the same mRNA with the use of different initiation codons. The long isoform (205 amino acids, 23/21 kD) is located mainly in the mitochondrial intermembrane space and exists under nonreducing and nondenaturing conditions as a homodimer and a heterodimer. The shorter isoform (125 amino acids, 15 kD), which lacks 80 amino acids at its N terminus compared to the longer isoform, is present predominantly in the nucleus (PMID: 19409522, 24880092, 21152698).