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验证数据展示

  • IHC staining of human testis using 25888-1-AP

    IHC staining of human testis using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 40x lens).

  • IHC staining of mouse brain using 25888-1-AP

    IHC staining of mouse brain using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 25888-1-AP (AMHR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human testis using 25888-1-AP

    IHC staining of human testis using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 10x lens).

  • IHC staining of mouse brain using 25888-1-AP

    IHC staining of mouse brain using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 25888-1-AP (AMHR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human ovary tumor using 25888-1-AP

    IHC staining of human ovary tumor using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 40x lens).

  • IHC staining of human ovary tumor using 25888-1-AP

    IHC staining of human ovary tumor using 25888-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 25888-1-AP (AMHR2 Antibody) at dilution of 1:100 (under 10x lens).

AMHR2 Polyclonal antibody

AMHR2 Polyclonal Antibody for IHC, ELISA
Cat No. 25888-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA

别名

AMH type II receptor, AMHR, AMHR2, MIS type II receptor, MISR2, MISRII, MRII

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inhuman testis tissue, human ovary tumor tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

25888-1-AP targets AMHR2 in IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 AMHR2 fusion protein Ag22473 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 anti-Mullerian hormone receptor, type II
别名 AMH type II receptor, AMHR, AMHR2, MIS type II receptor, MISR2, MISRII, MRII
计算分子量 573 aa, 63 kDa
GenBank蛋白编号BC126316
基因名称 AMHR2
Gene ID (NCBI) 269
RRIDAB_3085826
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ16671
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Anti-Mullerian hormone (Amh) is the key factor in the regression of the Mullerian ducts that is secreted by the Sertoli cells of the testis. As a member of the transforming growth factor β family, Amh signals through a heterodimeric receptor complex consisting of two type I and two types II serine/threonine kinases receptors (J. Klatting, et. al, 2007). On ligand binding, Type II receptors phosphorylate and activate Type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. The Amh type II receptor (Amhr2) confers the specificity and is initially expressed in the coelomic epithelium next to the Mullerian ducts in both males and females (Zhan, y. et. al, 2006).

实验方案

Product Specific Protocols
IHC protocol for AMHR2 antibody 25888-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols