Angiopoietin 1 Recombinant antibody, PBS Only

Angiopoietin 1 Uni-rAbTM Recombinant Antibody for WB, FC (Intra), ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, FC (Intra), ELISA

Conjugate

Unconjugated

CloneNo.

240764D10

Cat no : 81990-4-PBS

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Synonyms

ANGPT1, ANG-1, ANG1, ANG 1, AGPT



产品信息

81990-4-PBS targets Angiopoietin 1 in WB, FC (Intra), ELISA applications and shows reactivity with human samples.

Tested Applications WB, FC (Intra), ELISA Application Description
Tested Reactivity human
Immunogen Angiopoietin 1 fusion protein Ag18829 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name angiopoietin 1
Synonyms ANGPT1, ANG-1, ANG1, ANG 1, AGPT
Calculated Molecular Weight 498 aa, 58 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC152411
Gene Symbol Angiopoietin 1
Gene ID (NCBI) 284
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ15389
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.