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验证数据展示

  • WB analysis of human placenta using 67577-1-Ig (same clone as 67577-1-PBS)

    WB analysis of human placenta using 67577-1-Ig (same clone as 67577-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 67577-1-Ig (ANGPTL4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67577-1-PBS in a different storage buffer formulation.

  • IF Staining of NIH/3T3 using 67577-1-Ig (same clone as 67577-1-PBS)

    IF Staining of NIH/3T3 using 67577-1-Ig (same clone as 67577-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using ANGPTL4 antibody (67577-1-Ig, Clone: 1D2H6 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67577-1-PBS in a different storage buffer formulation.

ANGPTL4 Monoclonal antibody, PBS Only

ANGPTL4 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 67577-1-PBS

产品说明书

CloneNo. 1D2H6

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

Angiopoietin-related protein 4, Angiopoietin-like protein 4, Angiopoietin related protein 4, Angiopoietin like protein 4, angiopoietin like 4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67577-1-PBS targets ANGPTL4 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 ANGPTL4 fusion protein Ag30070 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 angiopoietin-like 4
别名 Angiopoietin-related protein 4, Angiopoietin-like protein 4, Angiopoietin related protein 4, Angiopoietin like protein 4, angiopoietin like 4
计算分子量 45 kDa
观测分子量 45-50 kDa
GenBank蛋白编号BC023647
基因名称 ANGPTL4
Gene ID (NCBI) 51129
RRIDAB_2882790
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9BY76
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Angiopoietin-like protein 4 (ANGPTL4), a member of the angiopoietin-like protein subfamily, is a secretory protein that functions as an important modulator of glucose and lipid metabolism. ANGPTL4 inhibits lipoprotein lipase (LPL)-dependent lipolysis thereby limiting the uptake of free fatty acids. Overexpression of ANGPTL4 results in hypertriglyceridemia, while ANGPTL4 deficiency suppresses foam formation in macrophages and protects against atherosclerosis. ANGPTL4 may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. ANGPTL4 has three isoforms, 45 kDa, 41 kDa and 27 kDa.