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验证数据展示

  • WB analysis of mouse testis using 15091-1-AP (same clone as 15091-1-PBS)

    WB analysis of mouse testis using 15091-1-AP (same clone as 15091-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 15091-1-AP (TEM8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15091-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 15091-1-AP (same clone as 15091-1-PBS)

    IHC staining of human colon cancer using 15091-1-AP (same clone as 15091-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15091-1-AP (TEM8 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 15091-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 15091-1-AP (same clone as 15091-1-PBS)

    IHC staining of human colon cancer using 15091-1-AP (same clone as 15091-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 15091-1-AP (TEM8 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 15091-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 15091-1-AP (same clone as 15091-1-PBS)

    IF Staining of HeLa using 15091-1-AP (same clone as 15091-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol) fixed HeLa cells using 15091-1-AP (TEM8 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 15091-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ANTXR1 Polyclonal antibody, PBS Only

ANTXR1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 15091-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

15091-1-PBS targets ANTXR1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ANTXR1 fusion protein Ag4626 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 anthrax toxin receptor 1
别名
计算分子量 63 kDa
观测分子量 85 kDa, 80 kDa
GenBank蛋白编号BC012074
基因名称 ANTXR1
Gene ID (NCBI) 84168
RRIDAB_2056891
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H6X2
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tumor endothelial marker 8 (TEM8, ANTXR1) and capillary morphogenesis protein 2 (CMG2, ANTXR2) are the two well-characterized anthrax toxin receptors, each containing a von Willebrand factor A (vWA) domain responsible for anthrax protective antigen (PA) binding (PMID: 23271637). TEM8 is a highly-conserved single-pass cell-surface protein overexpressed on tumor-infiltrating vasculature, and is thought to play a positive role in endothelial cell activities related to angiogenesis (PMID: 11559528; 15777794 ). The long isoforms of TEM8 have been identified as an 80-85 kDa doublet, and experimental deglycosylation reduced the molecular mass to 70 kDa, indicating that TEM8 undergoes multiple glycosylations (PMID: 14871805; 15689409).