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AQP6 Recombinant antibody, PBS Only

AQP6 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240175F9

Cat no : 83322-3-PBS

Print datasheet

Synonyms

Aquaporin6, Aquaporin 6, AQP 6, 240175F9

验证数据展示

  • WB analysis using 83322-3-RR (same clone as 83322-3-PBS)

    WB analysis using 83322-3-RR (same clone as 83322-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83322-3-RR (AQP6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83322-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83322-3-RR

    Affinity and Kinetic Characterization of 83322-3-RR

    Biolayer interferometry (BLl) kinetic assays of 83322-3-RR against Human AQP6 were performed. The affinity constant is 0.749 nM.

产品信息

The immunogen of 83322-3-PBS is AQP6 Fusion Protein expressed in E. coli.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen AQP6 fusion protein Ag26845 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name aquaporin 6, kidney specific
Synonyms Aquaporin6, Aquaporin 6, AQP 6, 240175F9
Calculated Molecular Weight 29 kDa
Observed Molecular Weight34 kDa
GenBank Accession NumberNM_001652
Gene Symbol AQP6
Gene ID (NCBI) 363
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ13520
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

AQP6 (Aquaporin-6) has recently been identified as an intracellular vesicle water channel with anion permeability that is activated by low pH or HgCl2 (PMID: 12034750). It could be involved in physiological mechanisms of fluid movement, acid-base regulation, and/or anion transport. The calculated MW of AQP6 is 29 kDa, but the actual observed MW is around 35 kDa, which represents glycosylated AQP6 monomer forms (PMID: 19811639).