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ARHGDIB Monoclonal antibody, PBS Only

ARHGDIB Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3E7B7

Cat no : 66054-1-PBS

Print datasheet

Synonyms

ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2

验证数据展示

  • WB analysis using 66054-1-Ig (same clone as 66054-1-PBS)

    WB analysis using 66054-1-Ig (same clone as 66054-1-PBS)

    Various lysates (25μg/lane) were subjected to SDS PAGE followed by western blot with 66054-1-Ig (ARHGDIB antibody) at dilution of 1:200000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66054-1-Ig (ARHGDIB antibody) at dilution of 1:10000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66054-1-Ig (ARHGDIB antibody) at dilution of 1:10000 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using ARHGDIB antibody (66054-1-Ig, Clone: 3E7B7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using ARHGDIB antibody (66054-1-Ig, Clone: 3E7B7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

产品信息

66054-1-PBS targets ARHGDIB in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen ARHGDIB fusion protein Ag9091 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name Rho GDP dissociation inhibitor (GDI) beta
Synonyms ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2
Calculated Molecular Weight 201 aa, 23 kDa
Observed Molecular Weight 27 kDa
GenBank Accession NumberBC009200
Gene Symbol ARHGDIB
Gene ID (NCBI) 397
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP52566
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer.