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Species Reactivity
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验证数据展示

  • WB analysis using 66054-1-Ig (same clone as 66054-1-PBS)

    WB analysis using 66054-1-Ig (same clone as 66054-1-PBS)

    Various lysates (25μg/lane) were subjected to SDS PAGE followed by western blot with 66054-1-Ig (ARHGDIB antibody) at dilution of 1:200000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66054-1-Ig (ARHGDIB antibody) at dilution of 1:10000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IHC staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66054-1-Ig (ARHGDIB antibody) at dilution of 1:10000 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using ARHGDIB antibody (66054-1-Ig, Clone: 3E7B7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

  • IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    IF Staining of human tonsillitis using 66054-1-Ig (same clone as 66054-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using ARHGDIB antibody (66054-1-Ig, Clone: 3E7B7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66054-1-PBS in a different storage buffer formulation.

ARHGDIB Monoclonal antibody, PBS Only

ARHGDIB Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 66054-1-PBS

产品说明书

CloneNo. 3E7B7

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse, rat

应用

WB, IHC, IF-P, Indirect ELISA

别名

ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66054-1-PBS targets ARHGDIB in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ARHGDIB fusion protein Ag9091 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 Rho GDP dissociation inhibitor (GDI) beta
别名 ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2
计算分子量 201 aa, 23 kDa
观测分子量 27 kDa
GenBank蛋白编号BC009200
基因名称 ARHGDIB
Gene ID (NCBI) 397
RRIDAB_11045657
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP52566
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer.