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ASCC1 Polyclonal antibody, PBS Only

ASCC1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12301-1-PBS

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Synonyms

SMABF2, CGI18, CGI 18, ASCC 1, ASC1p50

验证数据展示

  • WB analysis using 12301-1-AP (same clone as 12301-1-PBS)

    WB analysis using 12301-1-AP (same clone as 12301-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12301-1-AP (ASCC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12301-1-PBS in a different storage buffer formulation.

产品信息

12301-1-PBS targets ASCC1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen ASCC1 fusion protein Ag2946 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name activating signal cointegrator 1 complex subunit 1
Synonyms SMABF2, CGI18, CGI 18, ASCC 1, ASC1p50
Calculated Molecular Weight 45.5 kDa
Observed Molecular Weight 45.5 kDa
GenBank Accession NumberBC012291
Gene Symbol ASCC1
Gene ID (NCBI) 51008
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ASCC1 (also known as p50) is a subunit of an uncharacterized complex, the activating signal co-integrator complex (ASCC). ASCC1 has been reported as regulator fo NF-kB pathway and potently inhibits the expression of NF-kB target genes. Mutations in ASCC1 in patients with Barrett esophagus (BE) have been identified as a risk factor of esophageal adenocarcinoma (EAC).