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验证数据展示

  • IHC staining of human brain using 23751-1-AP (same clone as 23751-1-PBS)

    IHC staining of human brain using 23751-1-AP (same clone as 23751-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23751-1-AP (ASCL1 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23751-1-PBS in a different storage buffer formulation.

  • WB analysis using 23751-1-AP (same clone as 23751-1-PBS)

    WB analysis using 23751-1-AP (same clone as 23751-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23751-1-AP (ASCL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23751-1-PBS in a different storage buffer formulation.

ASCL1 Polyclonal antibody, PBS Only

ASCL1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 23751-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Achaete-scute homolog 1, ASH1, ASH-1, bHLHa46, Class A basic helix-loop-helix protein 46

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

23751-1-PBS targets ASCL1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 ASCL1 fusion protein Ag19360 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 achaete-scute complex homolog 1 (Drosophila)
别名 Achaete-scute homolog 1, ASH1, ASH-1, bHLHa46, Class A basic helix-loop-helix protein 46
计算分子量 25 kDa
观测分子量25 kDa
GenBank蛋白编号BC003134
基因名称 ASCL1
Gene ID (NCBI) 429
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen Affinity purified
UNIPROT IDP50553
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.