验证数据展示
产品信息
66884-1-PBS targets ASF1A in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, rat |
免疫原 | ASF1A fusion protein Ag1233 种属同源性预测 |
宿主/亚型 | Mouse / IgG3 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) |
别名 | CGI-98, CGI 98, CCG1-interacting factor A, CCG1 interacting factor A, Anti-silencing function protein 1 homolog A |
计算分子量 | 204 aa, 23 kDa |
观测分子量 | 21-23 kDa |
GenBank蛋白编号 | BC010878 |
基因名称 | ASF1A |
Gene ID (NCBI) | 25842 |
RRID | AB_2882216 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9Y294 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Anti-silencing function 1, S.cerevisiae, homolog of A(ASF1A) is a histone chaperone that has a crucial role in the remodeling of chromatin structure during replication, DNA repair, and cellular senescence. It promotes chromation assembly in replication-dependent manner by cooperation with chromation assembly factor1(CAF-1), and cooperates with HIRA in replication-independent manner. It's required forthe fomation of senescence-associated heterochromation foci(SAHF) and efficient senescence-associated cell cycle exit.