验证数据展示
产品信息
66884-1-PBS targets ASF1A in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, rat samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, rat |
Immunogen | ASF1A fusion protein Ag1233 种属同源性预测 |
Host / Isotype | Mouse / IgG3 |
Class | Monoclonal |
Type | Antibody |
Full Name | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) |
Synonyms | CGI-98, CGI 98, CCG1-interacting factor A, CCG1 interacting factor A, Anti-silencing function protein 1 homolog A |
Calculated Molecular Weight | 204 aa, 23 kDa |
Observed Molecular Weight | 21-23 kDa |
GenBank Accession Number | BC010878 |
Gene Symbol | ASF1A |
Gene ID (NCBI) | 25842 |
RRID | AB_2882216 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9Y294 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Anti-silencing function 1, S.cerevisiae, homolog of A(ASF1A) is a histone chaperone that has a crucial role in the remodeling of chromatin structure during replication, DNA repair, and cellular senescence. It promotes chromation assembly in replication-dependent manner by cooperation with chromation assembly factor1(CAF-1), and cooperates with HIRA in replication-independent manner. It's required forthe fomation of senescence-associated heterochromation foci(SAHF) and efficient senescence-associated cell cycle exit.