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  • Featured Product
  • KD/KO Validated

ASS1 Monoclonal antibody, PBS Only

ASS1 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, pig

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1D1A11

Cat no : 66036-1-PBS

Print datasheet

Synonyms

Argininosuccinate synthase, argininosuccinate synthetase 1, ASS, ASS1, Citrulline aspartate ligase, CTLN1

验证数据展示

  • IF Staining of MCF-7 using 66036-1-Ig (same clone as 66036-1-PBS)

    IF Staining of MCF-7 using 66036-1-Ig (same clone as 66036-1-PBS)

    Immunofluorescent analysis of MCF-7 cells, using ASS1 antibody 66036-1-Ig at 1:50 dilution and Rhodamine-labeled goat anti-mouse IgG (red). This data was developed using the same antibody clone with 66036-1-PBS in a different storage buffer formulation.

  • WB analysis of pig liver using 66036-1-Ig (same clone as 66036-1-PBS)

    WB analysis of pig liver using 66036-1-Ig (same clone as 66036-1-PBS)

    pig liver tissue were subjected to SDS PAGE followed by western blot with 66036-1-Ig (ASS1 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66036-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 66036-1-Ig (same clone as 66036-1-PBS)

    IHC staining of human liver using 66036-1-Ig (same clone as 66036-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66036-1-Ig (ASS1 Antibody) at dilution of 1:500 (under 10x lens). This data was developed using the same antibody clone with 66036-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with ASS1 antibody included
  • IHC staining of human liver using 66036-1-Ig (same clone as 66036-1-PBS)

    IHC staining of human liver using 66036-1-Ig (same clone as 66036-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66036-1-Ig (ASS1 Antibody) at dilution of 1:500 (under 40x lens). This data was developed using the same antibody clone with 66036-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with ASS1 antibody included
Planning an IHC experiment? We recommend our IHCeasy ASS1 Ready-To-Use IHC Kit. ASS1 primary antibody included.

产品信息

66036-1-PBS targets ASS1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, pig samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, pig
Immunogen ASS1 fusion protein Ag9314 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name argininosuccinate synthetase 1
Synonyms Argininosuccinate synthase, argininosuccinate synthetase 1, ASS, ASS1, Citrulline aspartate ligase, CTLN1
Calculated Molecular Weight 412 aa, 47 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberBC009243
Gene Symbol ASS1
Gene ID (NCBI) 445
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP00966
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ASS1 is a rate-limiting enzyme in the urea cycle. Citrullinemia type I is an autosomal recessive disorder that is caused by a deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS1). Deficiency of ASS1 shows various clinical manifestations encompassing severely affected patients with fatal neonatal hyperammonemia as well as asymptomatic individuals with only a biochemical phenotype(PMID:19006241).