验证数据展示
产品信息
84578-3-PBS targets ATL3 in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | ATL3 fusion protein Ag10248 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | atlastin GTPase 3 |
别名 | EC:3.6.5.-, Atlastin-3, Atlastin 3, 241937G3 |
计算分子量 | 541 aa, 61 kDa |
观测分子量 | 58-61 kDa |
GenBank蛋白编号 | BC077727 |
基因名称 | ATL3 |
Gene ID (NCBI) | 25923 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q6DD88 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ATL3, belonging to a class of dynamin-like GTPase, was reported to mediate ER fusion. ATL3 is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. ATL3 functions as a receptor for ER-phagy, promoting tubular ER degradation upon starvation. Mutations in this gene may be associated with hereditary sensory neuropathy type IF.