ATM Monoclonal antibody

ATM Monoclonal Antibody for WB, ELISA
Cat No. 67586-1-Ig

产品说明书

CloneNo. 3E6F4

宿主/亚型

Mouse / IgG1

种属反应性

human, rat and More (1)

应用

WB, ELISA and More (1)

Serine-protein kinase ATM, EC:2.7.11.1, A-T mutated, A T mutated, 3E6F4

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, HSC-T6 cells, HEK-293 cells, HepG2 cells
Planning an IHC experiment? We recommend our IHCeasy ATM Ready-To-Use IHC Kit. ATM primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:5000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67586-1-Ig targets ATM in WB, IF, ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, rat
文献引用反应性human, rat, pig
免疫原 ATM fusion protein Ag30001 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 ataxia telangiectasia mutated
别名 Serine-protein kinase ATM, EC:2.7.11.1, A-T mutated, A T mutated, 3E6F4
观测分子量 310-350 kDa
GenBank蛋白编号BC137169
基因名称 ATM
Gene ID (NCBI) 472
RRIDAB_2882795
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13315
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. It is involved in mitogenic signal transduction, meiotic recombination, detection of DNA damage, and cell cycle control.

实验方案

Product Specific Protocols
WB protocol for ATM antibody 67586-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Food Chem Toxicol

DON entry into the nucleus induces DNA damage, apoptosis and cycle arrest in GES-1 cells

Authors - Silu Hou
ratIF,WB

CNS Neurosci Ther

Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosis

Authors - Qian Jiang
humanWB

J Mol Med (Berl)

High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage response

Authors - Jiajia Pan
pigWB

Signal Transduct Target Ther

In vivo evaluation of guide-free Cas9-induced safety risks in a pig model

Authors - Weikai Ge
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