验证数据展示
经过测试的应用
Positive WB detected in | mouse testis tissue |
Positive IHC detected in | human ovary tissue, human testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:200-1:1000 |
Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
19243-1-AP targets ATN1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | ATN1 fusion protein Ag5835 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | atrophin 1 |
别名 | ATN1, atrophin 1, B37, D12S755E, DRPLA, HRS, NOD |
计算分子量 | 125 kDa |
观测分子量 | 105-110 kDa |
GenBank蛋白编号 | BC051795 |
基因名称 | ATN1 |
Gene ID (NCBI) | 1822 |
RRID | AB_2878575 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P54259 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ATN1 also known as Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat.
实验方案
Product Specific Protocols | |
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WB protocol for ATN1 antibody 19243-1-AP | Download protocol |
IHC protocol for ATN1 antibody 19243-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |