Antizyme inhibitor 1 Polyclonal antibody

Antizyme inhibitor 1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat no : 11548-1-AP

Print datasheet

Synonyms

Antizyme inhibitor 1, AZIN1, OAZI, OAZIN, ODC1L, AZI, AZI1, AZIN 1



经过测试的应用

Positive WB detected inA549 cells, HepG2 cells, NCI-H1299 cells, PC-3 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11548-1-AP targets Antizyme inhibitor 1 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF, IHC
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen Antizyme inhibitor 1 fusion protein Ag2082 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name antizyme inhibitor 1
Synonyms Antizyme inhibitor 1, AZIN1, OAZI, OAZIN, ODC1L, AZI, AZI1, AZIN 1
Calculated Molecular Weight49.5 kDa
Observed Molecular Weight 50 kDa
GenBank Accession NumberBC019279
Gene Symbol AZIN1
Gene ID (NCBI) 51582
RRIDAB_2290243
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14977
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

AZIN1(Antizyme inhibitor 1) is also named as OAZI, OAZIN and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis, and playing a role in the regulation of polyamine synthesis (negative regulator of cellular polyamines).

实验方案

Product Specific Protocols
WB protocol for Antizyme inhibitor 1 antibody 11548-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cancer Cell

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.

Authors - Leng Han
humanWB

J Clin Invest

Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.

Authors - Anna Bianchi-Smiraglia
humanWB

Mol Ther

Targeting RNA Editing of Antizyme Inhibitor 1: a Potential Oligonucleotide-Based Antisense Therapy for Cancer.

Authors - Daryl Jin Tai Tay
ratWB

Theranostics

Crucial Role of miR-433 in Regulating Cardiac Fibrosis.

Authors - Lichan Tao
mouseWB,IHC

Kidney Int

The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway.

Authors - Li Rong R
humanIHC

FASEB J

The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.

Authors - Xiaoying Chai