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Acalisib

Acalisib (CAL-120) 是一种PI3Kδ的选择性抑制剂，其 IC50=12.7 nM。

CAS号

870281-34-8

分子式

C21H16FN7O

主要靶点

PI3K

仅限科研使用

Cat No : CM05935

Print datasheet

Synonyms

CAL-120|GS-9820

验证数据展示

  • CAS No.: 870281-34-8

    Acalisib
    CAS#: 870281-34-8

产品信息

Acalisib (GS-9820) is a potent and selective inhibitor of PI3Kδ.

CAS号 870281-34-8
分子式 C21H16FN7O
主要靶点 PI3K
主要通路 PI3K/Akt/mTOR信号通路
分子量 401.4
纯度 98.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 CAL-120|GS-9820

靶点活性

p110δ:14 nM

溶解度

DMSO:73 mg/mL(181.9 mM)

参考文献

1.Shugg RP, et al. J Biol Chem. 2013 Dec 6;288(49):35346-57.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2