Adiponectin receptor 1 Polyclonal antibody
Adiponectin receptor 1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | mouse brain tissue, rat brain tissue |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
22425-1-AP targets Adiponectin receptor 1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | Adiponectin receptor 1 fusion protein Ag18187 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | adiponectin receptor 1 |
Synonyms | ACDCR1, adiponectin receptor 1, Adiponectin receptor protein 1, ADIPOR1, CGI 45, CGI45, PAQR1, TESBP1A |
Calculated Molecular Weight | 375 aa, 43 kDa |
Observed Molecular Weight | 45 kDa |
GenBank Accession Number | BC010743 |
Gene Symbol | ADIPOR1 |
Gene ID (NCBI) | 51094 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q96A54 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin have been identified: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). They are seven-transmembrane domain receptors and mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is found in many tissues, being particularly abundant in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver (PMID: 24417942). AdipoR1 has a high affinity for globular adiponectin and a very low affinity for full-length adiponectin. AdipoR2 has an intermediate affinity for both forms.
实验方案
Product Specific Protocols | |
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WB protocol for Adiponectin receptor 1 antibody 22425-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |