Aristolochic acid A

Aristolochic acid A (TR 1736) 是植物提取物 Aristolochic acids 的主要成分,主要存在于 Aristolochia 和 Asarum 草本植物中。它降低人细胞中膀胱癌相关BLCAP 基因表达。它显著降低激活蛋白1 (AP-1) 和NF-κB 活性。

CAS号

313-67-7

分子式

C17H11NO7

主要靶点

Others|NF-κB

仅限科研使用

Cat No : CM00621

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Synonyms

Aristolochic Acid|Aristolochine|Aristolochic Acid I|马兜铃酸|TR 1736|Aristolochin



产品信息

Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.

CAS号 313-67-7
分子式 C17H11NO7
主要靶点 Others|NF-κB
主要通路 NF-κB信号通路|其他
分子量 341.27
纯度 99.97%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Aristolochic Acid|Aristolochine|Aristolochic Acid I|马兜铃酸|TR 1736|Aristolochin

溶解度

DMSO:3.41 mg/mL (10 mM),Sonification is recommended.

参考文献

1.Ma L, et al. J Ethnopharmacol. 2015 Aug 22;172:430-5.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2