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Beta Arrestin 1 Recombinant antibody, PBS Only (Detector)

Beta Arrestin 1 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240974C3

Cat no : 83837-1-PBS

Print datasheet

Synonyms

ARRB1, ARR1, ARR 1, ARB2, ARB1

验证数据展示

  • WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83837-1-RR (Beta Arrestin 1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

  • WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 83837-1-RR (Arrestin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00811-2

    Cytometric bead array standard curve of MP00811-2

    Cytometric bead array standard curve of MP00811-2, Arrestin Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83837-2-PBS. Detection antibody: 83837-1-PBS. Standard: Ag7608. Range: 0.625-80 ng/mL.

  • Affinity and Kinetic Characterization of 83837-1-RR

    Affinity and Kinetic Characterization of 83837-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83837-1-RR against Human Beta Arrestin 1 were performed. The affinity constant is 0.759 nM.

Planning an IHC experiment? We recommend our IHCeasy ARRB1 Ready-To-Use IHC Kit. ARRB1 primary antibody included.

产品信息

83837-1-PBS targets Beta Arrestin 1 as part of a matched antibody pair:

MP00811-2: 83837-2-PBS capture and 83837-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Beta Arrestin 1 fusion protein Ag7608 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name arrestin, beta 1
Synonyms ARRB1, ARR1, ARR 1, ARB2, ARB1
Calculated Molecular Weight 47 kDa
Observed Molecular Weight47-55 kDa
GenBank Accession NumberBC003636
Gene Symbol Beta Arrestin 1
Gene ID (NCBI) 408
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP49407
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).