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验证数据展示

  • WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83837-1-RR (Beta Arrestin 1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

  • WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 83837-1-RR (Arrestin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00811-2

    Cytometric bead array standard curve of MP00811-2

    Cytometric bead array standard curve of MP00811-2, Beta Arrestin 1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83837-2-PBS. Detection antibody: 83837-1-PBS. Standard: Ag7608. Range: 0.625-80 ng/mL.

  • Affinity and Kinetic Characterization of 83837-1-PBS

    Affinity and Kinetic Characterization of 83837-1-PBS

    Biolayer interferometry (BLl) kinetic assay of 83837-1-PBS against Human Beta Arrestin 1 was performed. The affinity constant is 1.40 nM.

  • Affinity and Kinetic Characterization of 83837-1-RR

    Affinity and Kinetic Characterization of 83837-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83837-1-RR against Human Beta Arrestin 1 were performed. The affinity constant is 0.759 nM.

Beta Arrestin 1 Recombinant antibody, PBS Only (Detector)

Beta Arrestin 1 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 83837-1-PBS

产品说明书

CloneNo. 240974C3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Cytometric bead array, Indirect ELISA

别名

ARRB1, ARR1, ARR 1, ARB2, ARB1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy ARRB1 Ready-To-Use IHC Kit. ARRB1 primary antibody included.

产品信息

83837-1-PBS targets Beta Arrestin 1 as part of a matched antibody pair:

MP00811-2: 83837-2-PBS capture and 83837-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Beta Arrestin 1 fusion protein Ag7608 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 arrestin, beta 1
别名 ARRB1, ARR1, ARR 1, ARB2, ARB1
计算分子量 47 kDa
观测分子量47-55 kDa
GenBank蛋白编号BC003636
基因名称 Beta Arrestin 1
Gene ID (NCBI) 408
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP49407
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).