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Species Reactivity
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验证数据展示

  • WB analysis of mouse liver using 12080-1-AP (same clone as 12080-1-PBS)

    WB analysis of mouse liver using 12080-1-AP (same clone as 12080-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 12080-1-AP (B7‑H4 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12080-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 12080-1-AP (same clone as 12080-1-PBS)

    IHC staining of human ovary tumor using 12080-1-AP (same clone as 12080-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 12080-1-AP (B7‑H4 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12080-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with VTCN1 antibody included

B7‑H4 Polyclonal antibody, PBS Only

B7‑H4 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12080-1-PBS

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

VTCN1, B7S1, B7-H4, B7H4, B7h.5

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy VTCN1 Ready-To-Use IHC Kit. VTCN1 primary antibody included.

产品信息

12080-1-PBS targets B7‑H4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen B7‑H4 fusion protein Ag2712 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name V-set domain containing T cell activation inhibitor 1
Synonyms VTCN1, B7S1, B7-H4, B7H4, B7h.5
Calculated Molecular Weight 282 aa, 31 kDa
Observed Molecular Weight 55-65 kDa
GenBank Accession NumberBC065717
Gene Symbol B7-H4
Gene ID (NCBI) 79679
RRIDAB_2877822
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ7Z7D3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

B7‑H4 also named VTCN1, B7X, or B7S1 is a 282 amino acid protein, which contains 2 immunoglobulin-like domains and belongs to the immunoglobulin superfamily. B7‑H4 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. B7‑H4 is a single-pass type I membrane protein, which is over-expressed in breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The predicted molecular weight of B7‑H4 is 31 kDa. The glycosylated B7‑H4 is 50 to 80 kDa, and the non-glycosylated form is 28 kDa.