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B7H6 Recombinant antibody, PBS Only

B7H6 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

240808F7

Cat no : 83908-3-PBS

Print datasheet

Synonyms

NCR3LG1, Natural cytotoxicity triggering receptor 3 ligand 1, B7 homolog 6, B7 H6, 240808F7

验证数据展示

  • WB analysis using 83908-3-RR (same clone as 83908-3-PBS)

    WB analysis using 83908-3-RR (same clone as 83908-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83908-3-RR (B7H6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83908-3-PBS in a different storage buffer formulation.

产品信息

The immunogen of 83908-3-PBS is B7H6 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name hypothetical protein DKFZp686O24166
Synonyms NCR3LG1, Natural cytotoxicity triggering receptor 3 ligand 1, B7 homolog 6, B7 H6, 240808F7
Calculated Molecular Weight51 kDa
Observed Molecular Weight75-80 kDa
GenBank Accession NumberBC136800
Gene Symbol B7H6
Gene ID (NCBI) 374383
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ68D85
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

B7-H6, also known as NCR3LG1, is a member of the B7 family of immunoreceptors. It is a 454-aa-long type I transmembrane protein consisting of an extracellular region, a transmembrane segment, and a cytoplasmic domain which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), an SH2-binding domain, and an SH3-binding motif. B7-H6 triggers NKp30-mediated activation of human NK cells (PMID: 19528259). It has been reported that B7H6 is expressed in various types of tumor cells and plays a prominent role in natural killer cell immunosurveillance (PMID: 35697295). The apparent molecular weight of B7-H6 is larger than the calculated molecular weight of 51 kDa due to glycosylation (PMID: 19528259).