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  • Featured Product
  • KD/KO Validated

BACH2 Polyclonal antibody, PBS Only

BACH2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 27635-1-PBS

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Synonyms

验证数据展示

  • WB analysis of Daudi using 27635-1-AP (same clone as 27635-1-PBS)

    WB analysis of Daudi using 27635-1-AP (same clone as 27635-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 27635-1-AP (BACH2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27635-1-PBS in a different storage buffer formulation.

产品信息

27635-1-PBS targets BACH2 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen BACH2 fusion protein Ag26526 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name BTB and CNC homology 1, basic leucine zipper transcription factor 2
Synonyms
Calculated Molecular Weight 93 kDa
Observed Molecular Weight 120-130 kDa
GenBank Accession NumberNM_001170794
Gene Symbol BACH2
Gene ID (NCBI) 60468
RRIDAB_2880934
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BACH2, also named as Transcription regulator protein BACH2, is a 841 amino acid protein, which is widely expressed within the B-lymphoid lineage, except in plasma cells. BACH2 contains an N-terminal BTB domain involved in its transcriptional function, but instead of having zinc fingers at the C-terminus, it binds to DNA through a basic leucine zipper motif. BACH2 binds DNA consensus sequences, termed MARE motifs, by forming a heterodimer with small leucine zipper MAF proteins such as MAFK, MAFG, and MAFF. The calculated molecular weight of BACH2 is 92 kDa, but the post-modifiction of BACH2 is about 120-130 kDa. (PMID: 24277074 )