BAK Polyclonal antibody

BAK Polyclonal Antibody for ELISA
Cat No. 14673-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat and More (2)

应用

ELISA and More (3)

Apoptosis regulator BAK, BAK, BAK LIKE, BAK1, CDN1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy BAK Ready-To-Use IHC Kit. BAK primary antibody included.

产品信息

14673-1-AP targets BAK in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 ELISA Application Description
文献引用应用WB, IF, IHC
经测试反应性 human, mouse, rat
文献引用反应性human, mouse, rat, chicken, sheep
免疫原 BAK fusion protein Ag6354 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 BCL2-antagonist/killer 1
别名 Apoptosis regulator BAK, BAK, BAK LIKE, BAK1, CDN1
计算分子量 23 kDa
GenBank蛋白编号BC004431
基因名称 BAK1
Gene ID (NCBI) 578
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ16611
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BAK1, also named as BAK, BCL2L7 and CDN1, belongs to the Bcl-2 family. In the presence of an appropriate stimulus, BAK1 accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. (PMID:17157251) BAK1 gene product primarily enhances apoptotic cell death following an appropriate stimulus. It can inhibit cell death in an Epstein-Barr virus-transformed cell line.

发表文章

SpeciesApplicationTitle
mouseWB,IF

Nat Commun

Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA

Authors - Ayesha Sen
chickenWB

Sci Total Environ

MitomiR-1736-3p regulates copper-induced mitochondrial pathway apoptosis by inhibiting AATF in chicken hepatocytes

Authors - Yuanxu Li
humanWB

Oncotarget

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice.

Authors - Weiqi Dai
mouseWB

Mol Ther Nucleic Acids

lncRNA MIRF Promotes Cardiac Apoptosis through the miR-26a-Bak1 Axis.

Authors - Xiaomin Su
mouseWB

J Proteome Res

PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.

Authors - Wang Hui H
humanWB

Biochem Pharmacol

alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

Authors - Chen Wei W
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