验证数据展示
发表文章中的应用
| WB | See 7 publications below |
| IHC | See 1 publications below |
产品信息
16100-1-AP targets BAMBI in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IHC |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 | BAMBI fusion protein Ag8974 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) |
| 别名 | BAMBI, Non metastatic gene A protein |
| 计算分子量 | 260 aa, 29 kDa |
| GenBank蛋白编号 | BC019252 |
| 基因名称 | BAMBI |
| Gene ID (NCBI) | 25805 |
| RRID | AB_10807097 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q13145 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
BAMBI (BMP and activin membrane-bound inhibitor homolog) is a transmembrane protein and modulator of paracrine factors that regulate adipogenesis, including transforming growth factor (TGF) superfamily members (TGF-β and BMP) and Wnt. BAMBI is a type I TGFβ receptor antagonist and contributes to endothelial and vascular homeostasis. BAMBI deregulation has been involved in the pathogenesis of various human pathologies, such as tumor progression andmetastatic capability, pathological fibrosis and metaplastic bone formation.
发表文章
| Species | Application | Title |
|---|---|---|
J Cell Mol Med Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis. | ||
Sci Rep The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis. | ||
Toxicology Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. | ||
PLoS One Effect of miR-20b on Apoptosis, Differentiation, the BMP Signaling Pathway and Mitochondrial Function in the P19 Cell Model of Cardiac Differentiation In Vitro. | ||
J Dermatol miR-205-5p inhibits psoriasis-associated proliferation and angiogenesis: Wnt/β-catenin and mitogen-activated protein kinase signaling pathway are involved. | ||
J Cancer Exosomal miR-17-5p promotes angiogenesis in nasopharyngeal carcinoma via targeting BAMBI. |