验证数据展示
产品信息
82910-2-PBS targets BAZ2A in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IF/ICC, FC (Intra), Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | BAZ2A fusion protein Ag33963 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | bromodomain adjacent to zinc finger domain, 2A |
Synonyms | WALp3, TTF I interacting protein 5, TIP5, KIAA0314, hWALp3 |
Calculated Molecular Weight | 211 kDa |
Observed Molecular Weight | 250-270 kDa |
GenBank Accession Number | NM_013449.4 |
Gene Symbol | BAZ2A |
Gene ID (NCBI) | 11176 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9UIF9 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
BAZ2A (bromodomain adjacent to zinc finger domain 2A), also known as TIP5. It is expected to be located in nucleus, and the protein is expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. BAZ2A is an epigenetic regulator affecting transcription of ribosomal RNA, it is also a regulatory subunit of the ATP-dependent NoRC-1 and NoRC-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair (PubMed:28801535). The calculated molecular weight of BAZ2A is 210 kDa.