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验证数据展示

  • IF Staining of hTERT-RPE1 using 66136-1-Ig (same clone as 66136-1-PBS)

    IF Staining of hTERT-RPE1 using 66136-1-Ig (same clone as 66136-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed hTERT-RPE1 cells using BBS5 antibody (66136-1-Ig, Clone: 4G8E12 ) at dilution of 1:3511 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 66136-1-PBS in a different storage buffer formulation.

  • WB analysis of human brain using 66136-1-Ig (same clone as 66136-1-PBS)

    WB analysis of human brain using 66136-1-Ig (same clone as 66136-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 66136-1-Ig (BBS5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66136-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 66136-1-Ig (same clone as 66136-1-PBS)

    IHC staining of mouse kidney using 66136-1-Ig (same clone as 66136-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 66136-1-Ig (BBS5 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66136-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 66136-1-Ig (same clone as 66136-1-PBS)

    IHC staining of mouse kidney using 66136-1-Ig (same clone as 66136-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 66136-1-Ig (BBS5 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66136-1-PBS in a different storage buffer formulation.

BBS5 Monoclonal antibody, PBS Only

BBS5 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66136-1-PBS

产品说明书

CloneNo. 4G8E12

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

Bardet-Biedl syndrome 5 protein, Bardet Biedl syndrome 5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66136-1-PBS targets BBS5 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 BBS5 fusion protein Ag6844 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 Bardet-Biedl syndrome 5
别名 Bardet-Biedl syndrome 5 protein, Bardet Biedl syndrome 5
计算分子量 39 kDa
观测分子量 39 kDa
GenBank蛋白编号BC044593
基因名称 BBS5
Gene ID (NCBI) 129880
RRIDAB_2881535
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ8N3I7
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BBS5 encodes a protein that has been directly linked to Bardet-Biedl syndrome. Bardet-Biedl syndrome (BBS) is an autosomal recessive condition characterised by rod-cone dystrophy, postaxial polydactyly, central obesity, mental retardation, hypogonadism, and renal dysfunction. Other associated clinical findings in BBS patients include diabetes, hypertension and congenital heart defects. BBS expression varies both within and between families and diagnosis is often difficult. Experimentation in non-human eukaryotes suggests that BBS5 is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.