验证数据展示
产品信息
82956-1-PBS targets BCAN in FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | FC (Intra), Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | BCAN fusion protein Ag13596 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | brevican |
别名 | Brevican, 230126D6, BEHAB, Brain-enriched hyaluronan-binding protein, Brevican core protein |
计算分子量 | 99 kDa |
GenBank蛋白编号 | BC010571 |
基因名称 | BCAN |
Gene ID (NCBI) | 63827 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q96GW7 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Brevican is a brain-specific proteoglycan belonging to the aggrecan family that share a number of structural features. Brevican contains a hyaluronic acid-binding domain in its N-terminus and a lectin-like domain in its C-terminus. Expression of brevican is highly specific in the brain and increases as the brain develops. It may play a role in maintaining the extracellular environment of mature brain as a major constituent of the adult brain extracellular matrix (PMID:9117262). Brevican core protein exists as a 145 kDa full-length form and a 80 kDa N terminally truncated form (PMID: 8144512). This antibody can recognize the 72 kDa isoform of target.