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验证数据展示

  • Cytometric bead array standard curve of MP50570-1

    Cytometric bead array standard curve of MP50570-1

    Cytometric bead array standard curve of MP50570-1, BCKDHB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68596-2-PBS. Detection antibody: 68596-1-PBS. Standard:Ag33802. Range: 0.391-100 ng/mL.

  • Cytometric bead array standard curve of MP50570-3

    Cytometric bead array standard curve of MP50570-3

    Cytometric bead array standard curve of MP50570-3, BCKDHB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68596-4-PBS. Detection antibody: 68596-1-PBS. Standard:Ag33802. Range: 1.563-100 ng/mL.

BCKDHB Monoclonal antibody, PBS Only (Detector)

BCKDHB Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Cat No. 68596-1-PBS

Print datasheet

CloneNo. 1D12C7

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

Cytometric bead array, Indirect ELISA

Synonyms

E1B, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDH E1-beta, BCKDE1B, 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

68596-1-PBS targets BCKDHB as part of a matched antibody pair:

MP50570-1: 68596-2-PBS capture and 68596-1-PBS detection (validated in Cytometric bead array)

MP50570-3: 68596-4-PBS capture and 68596-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen BCKDHB fusion protein Ag33802 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name branched chain keto acid dehydrogenase E1, beta polypeptide
Synonyms E1B, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDH E1-beta, BCKDE1B, 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
Calculated Molecular Weight 392 aa, 43 kDa
Observed Molecular Weight35-37 kDa
GenBank Accession NumberBC040139
Gene Symbol BCKDHB
Gene ID (NCBI) 594
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP21953
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Branched-chain alpha-keto acid dehydrogenase E1 component beta chain (BCKDHB; BCKDE1B; BCKDH E1-beta) is a subunit of the BCKDH complex, which is a mitochondrial enzyme in the degradation pathway for branched-chain amino acids (BCAA). Together with BCKDHA, BCKDHB forms the E1 subunit of this complex, whereas DBT and DLD are the E2 and E3 subunits, respectively. A deficiency of the BCKDH complex in humans causes maple syrup urine disease (MSUD), a severe neurometabolic disorder diagnosed by the detection alloisoleucine in plasma (MIM 248600). (PMID: 30709776)