验证数据展示
经过测试的应用
Positive WB detected in | HeLa cells, SW480 cells, HEK-293 cells, RAW 264.7 cells, MCF-7 cells, Jurkat cells, MOLT-4 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
68611-1-Ig targets BCOR in WB, ELISA applications and shows reactivity with Human, mouse samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | Human, mouse |
免疫原 | BCOR fusion protein Ag33785 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | BCL6 co-repressor |
别名 | ANOP2, BCOR, FLJ20285, FLJ38041, KIAA1575, MAA2, MCOPS2 |
计算分子量 | 1703 aa, 186 kDa |
观测分子量 | 186-200 kDa |
GenBank蛋白编号 | BC009675 |
基因名称 | BCOR |
Gene ID (NCBI) | 54880 |
RRID | AB_3085306 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q6W2J9 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
BCOR, a corepressor of BCL6, binds to transcriptional factors and specifically inhibits gene expression. BCOR plays a key role in the early embryonic development, mesenchymal stem cell function and hematopiesis. BCOR can associate with HDACs, the polycomb group protein, polycomb group Ring finger protein1/nervous system polycomb1 (PCGF1/NSPC1), histone demethylase, F-box- and leucine-rich repeat protein10(FBXL10). Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem.
实验方案
Product Specific Protocols | |
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WB protocol for BCOR antibody 68611-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |