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验证数据展示

  • WB analysis using 17895-1-AP (same clone as 17895-1-PBS)

    WB analysis using 17895-1-AP (same clone as 17895-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17895-1-AP (BHLHE40 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 17895-1-AP (same clone as 17895-1-PBS)

    IP experiment of HeLa using 17895-1-AP (same clone as 17895-1-PBS)

    IP result of anti-BHLHE40 (IP:17895-1-AP, 4ug; Detection:17895-1-AP 1:1000) with HeLa cells lysate 1800 ug. This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 17895-1-AP (BHLHE40 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 17895-1-AP (BHLHE40 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

BHLHE40 Polyclonal antibody, PBS Only

BHLHE40 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 17895-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

17895-1-PBS targets BHLHE40 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 BHLHE40 fusion protein Ag12236 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 basic helix-loop-helix family, member e40
别名
计算分子量 412 aa, 46 kDa
观测分子量 46-50 kDa
GenBank蛋白编号BC082238
基因名称 BHLHE40
Gene ID (NCBI) 8553
RRIDAB_2065351
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14503
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BHLHE40 (Basic Helix-Loop-Helix Family Member E40), also known as BHLHB2, STRA13, DEC1, or SHARP2, is a member of the basic helix-loop-helix (bHLH) protein family, a large superfamily of transcriptional regulators expressed in many organisms. BHLHE40 is known to regulate a wide variety of essential cellular processes, including cell cycle, cellular proliferation, programmed cell death, cellular development and differentiation, as well as circadian rhythms (PMID: 34551158). It is reported that BHLHE40 is overexpressed in gastric, breast, and brain tumors; and downregulated in colorectal, esophageal, pancreatic and lung cancer (PMID: 32577154).