• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

BHLHE40 Polyclonal antibody, PBS Only

BHLHE40 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17895-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 17895-1-AP (same clone as 17895-1-PBS)

    WB analysis using 17895-1-AP (same clone as 17895-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17895-1-AP (BHLHE40 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 17895-1-AP (same clone as 17895-1-PBS)

    IP experiment of HeLa using 17895-1-AP (same clone as 17895-1-PBS)

    IP result of anti-BHLHE40 (IP:17895-1-AP, 4ug; Detection:17895-1-AP 1:1000) with HeLa cells lysate 1800 ug. This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 17895-1-AP (BHLHE40 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

  • IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    IHC staining of human endometrial cancer using 17895-1-AP (same clone as 17895-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 17895-1-AP (BHLHE40 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17895-1-PBS in a different storage buffer formulation.

产品信息

17895-1-PBS targets BHLHE40 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen BHLHE40 fusion protein Ag12236 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name basic helix-loop-helix family, member e40
Synonyms
Calculated Molecular Weight 412 aa, 46 kDa
Observed Molecular Weight 46-50 kDa
GenBank Accession NumberBC082238
Gene Symbol BHLHE40
Gene ID (NCBI) 8553
RRIDAB_2065351
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14503
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BHLHE40 (Basic Helix-Loop-Helix Family Member E40), also known as BHLHB2, STRA13, DEC1, or SHARP2, is a member of the basic helix-loop-helix (bHLH) protein family, a large superfamily of transcriptional regulators expressed in many organisms. BHLHE40 is known to regulate a wide variety of essential cellular processes, including cell cycle, cellular proliferation, programmed cell death, cellular development and differentiation, as well as circadian rhythms (PMID: 34551158). It is reported that BHLHE40 is overexpressed in gastric, breast, and brain tumors; and downregulated in colorectal, esophageal, pancreatic and lung cancer (PMID: 32577154).