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BI-6015

BI 6015 是肝细胞核因子 4α (HNF4α) 拮抗剂，可抑制已知 HNF4α 靶基因的表达。它利用 HNF4α 拮抗作用，降低胰岛素启动子活性，可用于研究癌症和糖尿病。

CAS号

93987-29-2

分子式

C15H13N3O4S

主要靶点

Others

仅限科研使用

Cat No : CM04629

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Synonyms

2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑

验证数据展示

  • CAS No.: 93987-29-2

    BI-6015
    CAS#: 93987-29-2

产品信息

BI 6015 is an antagonist of HNF4α. HNF4α is a nuclear receptor that regulates gene expression in the intestine cells, liver cells, and pancreas-β cells.

CAS号 93987-29-2
分子式 C15H13N3O4S
主要靶点 Others
主要通路 其他
分子量 331.35
纯度 99.81%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑

溶解度

DMSO:50 mg/mL (150.9 mM)

参考文献

1.Kiselyuk A, Lee SH, Farber-Katz S, et al. HNF4a Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter. Chem Biol, 2012, 19(7): 806-818

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2