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验证数据展示

  • WB analysis of pig bone marrow using 66383-1-Ig (same clone as 66383-1-PBS)

    WB analysis of pig bone marrow using 66383-1-Ig (same clone as 66383-1-PBS)

    pig bone marrow tissue were subjected to SDS PAGE followed by western blot with 66383-1-Ig (BMP2 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 66383-1-Ig (BMP2 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

  • WB analysis using 66383-1-Ig (same clone as 66383-1-PBS)

    WB analysis using 66383-1-Ig (same clone as 66383-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66383-1-Ig (BMP2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 66383-1-Ig (BMP2 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

BMP2 Monoclonal antibody, PBS Only

BMP2 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66383-1-PBS

产品说明书

CloneNo. 1C5C2

宿主/亚型

Mouse / IgG2a

种属反应性

human, pig

应用

WB, IHC, Indirect ELISA

别名

BMP 2, BMP2A, BMP-2, BMP-2A, BMP 2A

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66383-1-PBS targets BMP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, pig
免疫原 BMP2 fusion protein Ag13501 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 bone morphogenetic protein 2
别名 BMP 2, BMP2A, BMP-2, BMP-2A, BMP 2A
计算分子量 396 aa, 44 kDa
观测分子量 45 kDa
GenBank蛋白编号BC069214
基因名称 BMP2
Gene ID (NCBI) 650
RRIDAB_2881759
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP12643
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. Two band isofroms of BMP2 are present (PMID: 35846837).