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BMP2 Monoclonal antibody, PBS Only

BMP2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C5C2

Cat no : 66383-1-PBS

Print datasheet

Synonyms

BMP 2, BMP2A, BMP-2, BMP-2A, BMP 2A

验证数据展示

  • WB analysis of pig bone marrow using 66383-1-Ig (same clone as 66383-1-PBS)

    WB analysis of pig bone marrow using 66383-1-Ig (same clone as 66383-1-PBS)

    pig bone marrow tissue were subjected to SDS PAGE followed by western blot with 66383-1-Ig (BMP2 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 66383-1-Ig (BMP2 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

  • WB analysis using 66383-1-Ig (same clone as 66383-1-PBS)

    WB analysis using 66383-1-Ig (same clone as 66383-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66383-1-Ig (BMP2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    IHC staining of human small intestine using 66383-1-Ig (same clone as 66383-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 66383-1-Ig (BMP2 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66383-1-PBS in a different storage buffer formulation.

产品信息

66383-1-PBS targets BMP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, pig
Immunogen BMP2 fusion protein Ag13501 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name bone morphogenetic protein 2
Synonyms BMP 2, BMP2A, BMP-2, BMP-2A, BMP 2A
Calculated Molecular Weight 396 aa, 44 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC069214
Gene Symbol BMP2
Gene ID (NCBI) 650
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP12643
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. Two band isofroms of BMP2 are present (PMID: 35846837).