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  • Featured Product
  • KD/KO Validated

BMPR2 Polyclonal antibody, PBS Only

BMPR2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19087-1-PBS

Print datasheet

Synonyms

BMPR-2, BMPR II, BMPR 2, BMP type-2 receptor, BMP type II receptor

验证数据展示

  • IHC staining of human heart using 19087-1-AP (same clone as 19087-1-PBS)

    IHC staining of human heart using 19087-1-AP (same clone as 19087-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 19087-1-AP (BMPR2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19087-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 19087-1-AP (same clone as 19087-1-PBS)

    IHC staining of human heart using 19087-1-AP (same clone as 19087-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 19087-1-AP (BMPR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19087-1-PBS in a different storage buffer formulation.

  • FC experiment of PC-3 using 19087-1-AP (same clone as 19087-1-PBS)

    FC experiment of PC-3 using 19087-1-AP (same clone as 19087-1-PBS)

    1x10^6 PC-3 cells were intracellularly stained with 0.4 ug BMPR2 Polyclonal antibody (19087-1-AP) and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.4 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 19087-1-PBS in a different storage buffer formulation.

  • WB analysis of human heart using 19087-1-AP (same clone as 19087-1-PBS)

    WB analysis of human heart using 19087-1-AP (same clone as 19087-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 19087-1-AP (BMPR2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19087-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 19087-1-AP (same clone as 19087-1-PBS)

    IP experiment of mouse brain using 19087-1-AP (same clone as 19087-1-PBS)

    IP result of anti-BMPR2 (IP:19087-1-AP, 4ug; Detection:19087-1-AP 1:1500) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 19087-1-PBS in a different storage buffer formulation.

产品信息

19087-1-PBS targets BMPR2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen BMPR2 fusion protein Ag5868 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name bone morphogenetic protein receptor, type II (serine/threonine kinase)
Synonyms BMPR-2, BMPR II, BMPR 2, BMP type-2 receptor, BMP type II receptor
Calculated Molecular Weight 115 kDa
Observed Molecular Weight 120 kDa
GenBank Accession NumberBC052985
Gene Symbol BMPR2
Gene ID (NCBI) 659
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13873
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. The dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form, and 150 kD dimer.