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验证数据展示

  • IHC staining of human colon cancer using 51009-2-AP (same clone as 51009-2-PBS)

    IHC staining of human colon cancer using 51009-2-AP (same clone as 51009-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 51009-2-AP (BRD7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BRD7 antibody included
  • IHC staining of human cervical cancer using 51009-2-AP (same clone as 51009-2-PBS)

    IHC staining of human cervical cancer using 51009-2-AP (same clone as 51009-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 51009-2-AP (BRD7 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BRD7 antibody included
  • WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

  • WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

BRD7 Polyclonal antibody, PBS Only

BRD7 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 51009-2-PBS

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy BRD7 Ready-To-Use IHC Kit. BRD7 primary antibody included.

产品信息

51009-2-PBS targets BRD7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen BRD7 fusion protein Ag3911 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name bromodomain containing 7
Synonyms
Calculated Molecular Weight 651 aa, 74 kDa
Observed Molecular Weight 70-74 kDa
GenBank Accession NumberBC050728
Gene Symbol BRD7
Gene ID (NCBI) 29117
RRIDAB_2259226
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NPI1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.