验证数据展示
产品信息
16995-1-AP targets BTBD10 in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | BTBD10 fusion protein Ag10684 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | BTB (POZ) domain containing 10 |
| 别名 | BTB (POZ) domain containing 10, BTBD10, GMRP 1, GMRP1 |
| 计算分子量 | 475 aa, 54 kDa |
| GenBank蛋白编号 | BC017072 |
| 基因名称 | BTBD10 |
| Gene ID (NCBI) | 84280 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BSF8 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
BTBD10 is a novel Akt-interacting protein with a BTB/POZ domain,which equally binds to any Akt. BTBD10 appears to behave as a suppressor of cell death including neuronal cell death related to ALS and an enhancer of cell growth via its positive regulation of Akt phosphorylation. The protein is expressed ubiquitously in vivo, distributing in cells as a unique cytoplasmic filamentous around the nucleus. This antibody 16995-1-AP is raised against C-terminal 220 amino acids of full protein.