BTNL2 Polyclonal antibody

BTNL2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 25110-1-AP

Print datasheet

Synonyms

BTL II, BTNL2, Butyrophilin like protein 2, HSBLMHC1, SS2



经过测试的应用

Positive WB detected inHL-60 cells, mouse kidney tissue, HepG2 cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

25110-1-AP targets BTNL2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human, mouse
Cited Reactivityhuman
Immunogen BTNL2 fusion protein Ag18803 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name butyrophilin-like 2 (MHC class II associated)
Synonyms BTL II, BTNL2, Butyrophilin like protein 2, HSBLMHC1, SS2
Calculated Molecular Weight 455 aa, 50 kDa
Observed Molecular Weight 65 kDa
GenBank Accession NumberBC127642
Gene Symbol BTNL2
Gene ID (NCBI) 56244
RRIDAB_2879902
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UIR0
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Butyrophilin-like protein 2 (BTNL2) is a transmembrane immunoregulatory protein that is highly expressed in the gastrointestinal tract. BTNL2 belongs to the butyrophilin-like family of proteins, and several of the butyrophilins and butyrophilin-like proteins, such as BTN2A1, BTN3A1, skint-1, BTNL1 and BTNL6, have been shown to play an essential role in regulating γδ T cell development and differentiation.

实验方案

Product Specific Protocols
WB protocol for BTNL2 antibody 25110-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Nat Commun

Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells.

Authors - Yanyun Du