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BZRAP1 Polyclonal antibody

BZRAP1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 28241-1-AP

Print datasheet

Synonyms

BZRAP1, DKFZp686F02123, KIAA0612, PBR IP, PRAX 1, PRAX1, RBP1, RIM BP1, RIMBP1, RIMS binding protein 1

验证数据展示

  • WB analysis of Neuro-2a using 28241-1-AP

    WB analysis of Neuro-2a using 28241-1-AP

    Neuro-2a cells were subjected to SDS PAGE followed by western blot with 28241-1-AP (BZRAP1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inNeuro-2a cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28241-1-AP targets BZRAP1 in WB, ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, mouse
Immunogen BZRAP1 fusion protein Ag28198 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name benzodiazapine receptor (peripheral) associated protein 1
Synonyms BZRAP1, DKFZp686F02123, KIAA0612, PBR IP, PRAX 1, PRAX1, RBP1, RIM BP1, RIMBP1, RIMS binding protein 1
Calculated Molecular Weight 1857 aa, 200 kDa
Observed Molecular Weight 200-235 kDa
GenBank Accession NumberBC146852
Gene Symbol BZRAP1
Gene ID (NCBI) 9256
RRIDAB_2881096
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO95153
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BZRAP1, also named as TSPOAP1 and PBR-associated protein 1 (PRAX-1), is a cytoplasmic protein of 1857 residues. It plays a key role in inflammation, neuroinflammation, mental and metabolic diseases, and cancer. BZRAP1 predominantly expressed in the central nervous system, pituitary gland, and thymus, specially abundant in the CA1 subfield of the hippocampus. Tumor necrosis factor receptor 1 (TNFR1), vascular cell adhesion molecule 1 (VCAM1), cyclic AMP response element-binding protein 1 (CREB1), T-cell receptor (TCR), nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NLRP3), DNA-dependent protein kinase (DNA-PK or PRKDC), and mitochondrial permeability transition pore (mPTP) were the major interaction partners of BZRAP1 (PMID: 34212002).

实验方案

Product Specific Protocols
WB protocol for BZRAP1 antibody 28241-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols