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Banoxantrone dihydrochloride

Banoxantrone dihydrochloride (AQ4N dihydrochloride) 是一种新型缺氧细胞毒素，通过 iNOS 依赖机制选择性地杀死缺氧细胞。

CAS号

252979-56-9

分子式

C22H30Cl2N4O6

主要靶点

Others

仅限科研使用

Cat No : CM21192

Print datasheet

Synonyms

AZD1689 2HCl|AQ4N dihydrochloride

验证数据展示

  • CAS No.: 252979-56-9

    Banoxantrone dihydrochloride
    CAS#: 252979-56-9

产品信息

Banoxantrone dihydrochloride (AQ4N dihydrochloride) 是一种新型缺氧细胞毒素，通过 iNOS 依赖机制选择性地杀死缺氧细胞。

CAS号 252979-56-9
分子式 C22H30Cl2N4O6
主要靶点 Others
主要通路 其他
分子量 517.4
纯度 98.93%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 AZD1689 2HCl|AQ4N dihydrochloride

溶解度

DMSO:10 mg/mL (19.33 mM),Sonification is recommended.,H2O:10 mg/mL (19.33 mM),Sonification is recommended.

参考文献

1.Williams KJ, et al. In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts. Mol Cancer Ther. 2009 Dec;8(12):3266-75.
2.Manley E Jr, et al. Impact of tumor blood flow modulation on tumor sensitivity to the bioreductive drug banoxantrone. J Pharmacol Exp Ther. 2013 Feb;344(2):368-77.
3.Hejmadi MV, et al. DNA damage following combination of radiation with the bioreductive drug AQ4N: possible selective toxicity to oxic and hypoxic tumour cells. Br J Cancer. 1996 Feb;73(4):499-505.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2