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Beta Arrestin 2 Recombinant antibody, PBS Only (Detector)

Beta Arrestin 2 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241470F8

Cat no : 82780-6-PBS

Print datasheet

Synonyms

ARRB2, β-Arrestin 2, BARR2, Arrestin beta-2, ARR2

验证数据展示

  • WB analysis using 82780-6-RR (same clone as 82780-6-PBS)

    WB analysis using 82780-6-RR (same clone as 82780-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82780-6-RR (Beta Arrestin 2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82780-6-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01125-3

    Cytometric bead array standard curve of MP01125-3

    Cytometric bead array standard curve of MP01125-3, Beta Arrestin 2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82780-5-PBS. Detection antibody: 82780-6-PBS. Standard: Ag0227. Range: 0.781-100 ng/mL.

  • Affinity and Kinetic Characterization of 82780-6-RR

    Affinity and Kinetic Characterization of 82780-6-RR

    Biolayer interferometry (BLl) kinetic assays of 82780-6-RR against Human Beta Arrestin 2 were performed. The affinity constant is below 1 pM.

产品信息

82780-6-PBS targets Beta Arrestin 2 as part of a matched antibody pair:

MP01125-3: 82780-5-PBS capture and 82780-6-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Beta Arrestin 2 fusion protein Ag0227 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name arrestin, beta 2
Synonyms ARRB2, β-Arrestin 2, BARR2, Arrestin beta-2, ARR2
Calculated Molecular Weight 46 kDa
Observed Molecular Weight47-50 kDa
GenBank Accession NumberBC007427
Gene Symbol Beta Arrestin 2
Gene ID (NCBI) 409
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP32121
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Beta Arrestin 2 is a member of arrestin/beta-arrestin protein family, which are expressed at high levels in the central nervous system (CNS) and play a critical role in the regulation of G-protein coupled receptors (GPCRs) including MOR. Beta Arrestin 2 is an adaptor protein that is important for the regulation of receptors belonging to both dopaminergic and opioid systems. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.